Effectiveness of a comprehensive model of a very low-calorie diet with meal replacement and liraglutide for weight reduction in patients with obesity
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Body Weight
Weight Loss

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Rosero, O., Pantoja, D., Pabón, N., & Ibarra, J. (2021). Effectiveness of a comprehensive model of a very low-calorie diet with meal replacement and liraglutide for weight reduction in patients with obesity. Revista Endocrino, 7(4), 244–247. https://doi.org/10.53853/encr.7.4.650


Introduction: In recent years, the prevalence of obesity has been growing worldwide, becoming a public health problem. Achieving a decrease in weight has become a challenge for both healthcare personnel as well as patients: a decrease of 5% to 10% in weight in obese or overweight patients has a positive impact on morbidity and mortality. This study describes the results of a therapeutic intervention program aimed at achieving weight loss in an obese population.

Methodology: a descriptive, retrospective study of a group of 63 patients who entered a comprehensive program of controlled caloric restriction, with the use of liraglutide titled, 3-month duration called The Balance Method, in the city of Pasto, Nariño, from April 2018 to December 2019.

Results: 77.7% were women and 22.3%, men, with a mean age of 43.4 years. On average, there was a decrease of 11.85% in body, a loss of body fat of 11.67% and a decrease in abdominal circumference of 13.2 cm; there were no statistically significant changes in lean body mass or basal metabolism.

Conclusion: The proposed methodology of a comprehensive multidisciplinary caloric restriction model with the use of liraglutida may be an effective strategy for significant short-term weight loss in obese patients, without statistically significant decrease in lean mass or muscle mass. your resting metabolic rate.

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